Microtubules (25nm dia, largest) Mitotic spindles during mitosis One end anchors to the microtubule organizing center (MTOC, such as centrosome and basal bodies) The other end is rapidly (de)polymerizing to change length Cell motility Cilia Flagella Tracks for the transport of organelles and secretory vesicles (incl. soma<->axon terminal in nerves, a process called axonal or axoplasmic transport) Involves kinesin and dynein Made of alpha and beta-tubulin which form a heterodimer, which then polymerize to form a sheet. Said sheet rolls up to form the microtubule DYNAMIC (can lengthen/shorten v frequently) Intermediate filaments (10nm dia) Structural/shape support, resist mechanical stress, anchor organelles, form nuclear lamina Composed of various keratinous proteins strung together into polymers PERMANENT Microfilaments (7nm dia, smallest) Gross movement of the cell (from within the cell) and changes in cell shape e.g. pinch the cell for celavage furropw formation (cell division) e.g. ameboid movement of MOs (pseudopod projections [pseudopodia] that grab material for ingestion) Composed of actin polymers twisted to form actin filaments DYNAMIC (can lengthen/shorten v frequently)